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Viruses

Viruses have been around since life began but they are 'of life', they are not technically 'alive' because they cannot themselves reproduce. They are extremely small - about 70 microns in diametre - and until the invention of electron microscopes in the 1930's their existance had only been inferred. 

To create copies of themselves they need a host cell with the necessary reproductive mechanisms. Over the millennia viruses have evolved the necessary mechanisms to penetrate cells, much like spermatozoa, and inject their DNA or RNA and capture the host's replication mechanisms so that the infected cell begins manufacturing thousands of virion (virus particle) clones of the invader. These then capture other nearby cells in the host animal or plant; or in similar bacteria.  Huge numbers of infected cells are usually destroyed in the process, sometimes killing the plant or animal.

 

c0487121 cell infected with covid 19 coronavirus particles sem web

Coronavirus particles (yellow) on the surface of a dying cell (that produced them)
Niaid/National Institutes of Health/Science Photo Library (from 
https://www.newscientist.com)

 

But animals plants and bacteria have become familiar with this threat and have in turn evolved means of dealing with or living with viruses to the extent that some are exploited for the benefit of the host.

In turn viruses evolve new strategies to perpetuate their reproduction. Thus new viruses arise from time to time, sometimes jumping from one species to another when an opportunity arises.

Many animals, including humans, have an immune system that has a memory of harmful viruses and means of neutralising them. Thus, once the animal has been infected and survived, the chances of reinfection are reduced.  Vaccines work by presenting our immune system with a harmless sample that allows it to recognise a particular harmful virus.

Since I first wrote this article the World has suffered a new viral pandemic.  It is a novel corona virus for which we have no established immunity and there is no vaccine.  At the end of June 2020 the Covi-19 virus has already killed half a million people.

It is estimated that this virus will no longer find sufficient vulnerable hosts to spread further after infecting around 70% of the populations in which it is spreading.  It has a case fatality rate of just under 1%, that is, of those who catch it just under one in a hundred die.  

Quarantine restrictions are in place in many countries to protect relatively uninfected areas, with local measures to eliminate 'hot spots'.  But the majority of the world's population, in excess of five billion, are in countries in which it is presently spreading.

Unless a vaccine is available soon it seems inevitable that many millions more will be killed.  The economic consequences are also dire.

 

 

 

 

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Travel

The United Kingdom

 

In May and Early June 2013 we again spent some time in the UK on our way to Russia. First stop London. On the surface London seems quite like Australia. Walking about the streets; buying meals; travelling on public transport; staying in hotels; watching TV; going to a play; visiting friends; shopping; going to the movies in London seems mundane compared to travel to most other countries.  Signs are in English; most people speak a version of our language, depending on their region of origin. Electricity is the same and we drive on the same side or the street.  Bott Wendy and I have lived in London in previous lives, so it's like another home.

But look as you might, nowhere in Australia is really like London.

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Fiction, Recollections & News

The Greatest Aviation Mystery of All Time

 

 

The search for Malaysia Airlines Flight 370 was finally called off in the first week of June 2018.

The flight's disappearance on the morning of 8 March 2014 has been described as the greatest aviation mystery of all time, surpassing the disappearance of Amelia Earhart in 1937.  Whether or no it now holds that record, the fruitless four year search for the missing plane is certainly the most costly in aviation history and MH370 has already spawned more conspiracy theories than the assassination of JFK; the disappearance of Australian PM Harold Holt; and the death of the former Princess Diana of Wales; combined.

Read more: The Greatest Aviation Mystery of All Time

Opinions and Philosophy

Holden - The Demise of an Iconic Brand

 

I drive a Holden. 

It’s my second. The first was a shiny black Commodore.  A V6 Lumina edition.

I have owned well over a dozen cars and driven a lot more, in numerous countries, but these are my first from General Motors.

The new one is a white Calais Sportswagon and it's the best car I've ever owned.

Based on the German Opel, it has traction control conferring impeccable braking and steering and ample power and acceleration even with four adults and luggage.  Add to that: leather seats; climate control; head-up display; voice commands for entertainment, phone and so on; and it's a luxurious ride.

Yet I’m starting to think that I can put an end to any car brand, just by buying one.

Holden finally ceased manufacturing in Australia just after my present model rolled off the production line.

Read more: Holden - The Demise of an Iconic Brand

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