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Viruses

Viruses have been around since life began but they are 'of life', they are not technically 'alive' because they cannot themselves reproduce. They are extremely small - about 70 microns in diametre - and until the invention of electron microscopes in the 1930's their existance had only been inferred. 

To create copies of themselves they need a host cell with the necessary reproductive mechanisms. Over the millennia viruses have evolved the necessary mechanisms to penetrate cells, much like spermatozoa, and inject their DNA or RNA and capture the host's replication mechanisms so that the infected cell begins manufacturing thousands of virion (virus particle) clones of the invader. These then capture other nearby cells in the host animal or plant; or in similar bacteria.  Huge numbers of infected cells are usually destroyed in the process, sometimes killing the plant or animal.

 

c0487121 cell infected with covid 19 coronavirus particles sem web

Coronavirus particles (yellow) on the surface of a dying cell (that produced them)
Niaid/National Institutes of Health/Science Photo Library (from 
https://www.newscientist.com)

 

But animals plants and bacteria have become familiar with this threat and have in turn evolved means of dealing with or living with viruses to the extent that some are exploited for the benefit of the host.

In turn viruses evolve new strategies to perpetuate their reproduction. Thus new viruses arise from time to time, sometimes jumping from one species to another when an opportunity arises.

Many animals, including humans, have an immune system that has a memory of harmful viruses and means of neutralising them. Thus, once the animal has been infected and survived, the chances of reinfection are reduced.  Vaccines work by presenting our immune system with a harmless sample that allows it to recognise a particular harmful virus.

Since I first wrote this article the World has suffered a new viral pandemic.  It is a novel corona virus for which we have no established immunity and there is no vaccine.  At the end of June 2020 the Covi-19 virus has already killed half a million people.

It is estimated that this virus will no longer find sufficient vulnerable hosts to spread further after infecting around 70% of the populations in which it is spreading.  It has a case fatality rate of just under 1%, that is, of those who catch it just under one in a hundred die.  

Quarantine restrictions are in place in many countries to protect relatively uninfected areas, with local measures to eliminate 'hot spots'.  But the majority of the world's population, in excess of five billion, are in countries in which it is presently spreading.

Unless a vaccine is available soon it seems inevitable that many millions more will be killed.  The economic consequences are also dire.

 

 

 

 

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Travel

The Greatest Dining Experience Ever in Bangkok

A short story

 

The Bangkok Sky-train, that repetition of great, grey megaliths of ferroconcrete looms above us.   

All along the main roads, under the overhead railway above, small igloo tents and market stalls provide a carnival atmosphere to Bangkok.  It’s like a giant school fete - except that people are getting killed – half a dozen shot and a couple of grenades lobbed-in to date.

Periodically, as we pass along the pedestrian thronged roads, closed to all but involved vehicles, we encounter flattop trucks mounted with huge video screens or deafening loud speakers. 

Read more: The Greatest Dining Experience Ever in Bangkok

Fiction, Recollections & News

The First Man on the Moon

 

 

 

 

At 12.56 pm on 21 July 1969 Australian Eastern Standard Time (AEST) Neil Armstrong became the first man to step down onto the Moon.  I was at work that day but it was lunchtime.  Workplaces did not generally run to television sets and I initially saw it in 'real time' in a shop window in the city.  

Later that evening I would watch a full replay at my parents' home.  They had a 'big' 26" TV - black and white of course.  I had a new job in Sydney having just abandoned Canberra to get married later that year.  My future in-laws, being of a more academic bent, did not have TV that was still regarded by many as mindless.

Given the early failures, and a few deaths, the decision to televise the event in 'real time' to the international public was taking a risk.  But the whole space program was controversial in the US and sceptics needed to be persuaded.

Read more: The First Man on the Moon

Opinions and Philosophy

In Defence of Secrecy

 

 

Julian Assange is in the news again. 

I have commented on his theories and his worries before.

I know no more than you do about his worries; except to say that in his shoes I would be worried too.  

But I take issue with his unqualified crusade to reveal the World’s secrets.  I disagree that secrets are always a bad thing.

Read more: In Defence of Secrecy

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